Article

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

2021-05-23

Abstract excerpt

The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of genetic variants associated with critical illness (n=35) or hospitalization (n=42) due to severe COVID-19 using genome-wide association summary from the Host Genetics Initiative. PheWAS analysis wa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b0613bf5-7341-51f7-a175-0f23604d57d8
DOI: 10.1101/2021.05.18.21257396

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran ProgramDOI 10.1101/2021.05.18.21257396Read

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program.Semantic proximity Read

A Phenome Wide Association Study of Severe COVID-19 Genetic Risk VariantsSemantic proximity Read

The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.Semantic proximity Read

A comprehensive knowledgebase of known and predicted human genetic variants associated with COVID-19 susceptibility and severitySemantic proximity Read

The genetic risk for COVID-19 severity is associated with defective innate immune responsesSemantic proximity Read

Integrative analyses identify susceptibility genes underlying COVID-19 hospitalizationSemantic proximity Read

Multi-Layered Genomic and Clinical Analysis Identifies Novel Variants, Co-Occurring Single Nucleotide Polymorphism Pairs, and Clinical Determinants of Host-Pathogen Interaction in COVID-19 Severity.Semantic proximity Read

Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization.Semantic proximity Read

A second update on mapping the human genetic architecture of COVID-19Semantic proximity Read

GWAS and meta-analysis identifies multiple new genetic mechanisms underlying severe Covid-19Semantic proximity Read

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severitySemantic proximity Read

A second update on mapping the human genetic architecture of COVID-19Semantic proximity Read