Article

Endothelial expression of ZBTB16 protects against cardiac aging

2025-10-08

Abstract excerpt

<h4>Background and aim</h4> Aging significantly increases the risk of cardiovascular diseases, characterized by progressive cardiac dysfunction. The vascular niche is crucial for maintaining cardiac homeostasis, yet endothelial cell (EC) impairment during aging remains poorly understood. This study investigates epigenetically regulated mechanisms mediating EC-dependent cardiac aging and identifies a critical role...

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Literature Corpus work: d32cb070-ba3e-5b3a-8f20-92ae04f6067d
DOI: 10.1101/2025.10.08.681100

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