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Article

Dynamic Covalent Disulfide Exchange Mediates Oral Delivery of Biomacromolecules

2024-03-08

Abstract excerpt

<title>Abstract</title> <p>The biological barriers present in the intestine thwart the absorption of orally delivered biologics, which, if overcome, would reduce the injection burdens for millions of patients. Here, we present a straightforward yet effective oral biologic formulation, which utilizes <italic>in-situ</italic> growing poly(disulfide)s as the sole excipient to circumvent all intestinal barriers in a...

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Literature Corpus work
d2e3da31-b4b4-53c5-8155-1b597ddbb6f2
DOI
10.21203/rs.3.rs-3616020/v1
Open publication

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Dynamic Covalent Disulfide Exchange Mediates Oral Delivery of BiomacromoleculesDOI 10.21203/rs.3.rs-3616020/v1
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