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<i>In vivo</i> fate of systemically administered encapsulin protein nanocages and implications for their use in targeted drug delivery

2023-07-18

Abstract excerpt

Encapsulins, self-assembling protein nanocages derived from prokaryotes, are promising nanoparticle-based drug delivery systems (NDDS). However, the in vivo behavior and fate of encapsulins are poorly understood. In this pre-clinical study, we probe the interactions between the model encapsulin from Thermotoga maritima (TmEnc) and key biological barriers encountered by NDDS. Here, a purified TmEnc formulation th...

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Identifiers and source

Literature Corpus work
a8c86340-7991-5955-88aa-cb8a12e74b38
DOI
10.1101/2023.07.16.549228
Open publication

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<i>In vivo</i> fate of systemically administered encapsulin protein nanocages and implications for their use in targeted drug deliveryDOI 10.1101/2023.07.16.549228
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