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Bioactive Metal-Phenolic Network and Prebiotic Hydrogel Synergize with Mesenchymal stem cell-derived extracellular vesicles for Microenvironment-Modulating Therapy of Inflammatory Bowel Disease

2026-08-10

Abstract excerpt

<title>Abstract</title> <p>Mesenchymal stem cell-derived extracellular vesicles (MVs) holds great promise for inflammatory bowel disease (IBD) therapy. However, oral delivery of MVs therapeutic efficacy is severely compromised by the harsh gastrointestinal environment and the hostile inflammatory milieu, characterized by excessive oxidative stress and dysbiosis. To surmount these biological barriers, we engineere...

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Literature Corpus work
84ac64f1-4471-588f-8e69-d076e9a40fd2
DOI
10.21203/rs.3.rs-10544945/v1
Open publication

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Bioactive Metal-Phenolic Network and Prebiotic Hydrogel Synergize with Mesenchymal stem cell-derived extracellular vesicles for Microenvironment-Modulating Therapy of Inflammatory Bowel DiseaseDOI 10.21203/rs.3.rs-10544945/v1
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