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Colon-Targeting pH-Responsive Bletilla striata Polysaccharide Coacervate Microdroplets for Ulcerative Colitis Therapy via Macrophage Reprogramming

2026-06-30

Abstract excerpt

<title>Abstract</title> <p> Ulcerative colitis (UC) is an immune-mediated chronic inflammatory bowel disease that severely impairs patients' quality of life. Current clinical treatments urgently require efficient colon-targeted drug delivery systems to overcome the limitations of traditional therapeutics, such as poor lesion-targeting efficacy and significant systemic toxicity. Herein, we constructed a novel pH-...

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Literature Corpus work
c63e0b64-d506-58a6-b3c9-b5990ad30ef9
DOI
10.21203/rs.3.rs-10116278/v1
Open publication

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Colon-Targeting pH-Responsive Bletilla striata Polysaccharide Coacervate Microdroplets for Ulcerative Colitis Therapy via Macrophage ReprogrammingDOI 10.21203/rs.3.rs-10116278/v1
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