Article

A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

2024-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Amyloid β (Aβ) forms aggregates in the Alzheimer’s disease brain and is well known for its pathological roles. Recent studies show that it also regulates neuronal physiology in the healthy brain. Whether Aβ also regulates glial physiology in the normal brain, however, has remained unclear. In this article, we describe the discovery of a novel signaling pathway activated by the monomeric form of...

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Literature Corpus work: d237b5fa-612f-535a-89d2-1de77893d782
DOI: 10.1101/2024.06.13.598890

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