Article
Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury
2018-05-31
Abstract excerpt
<h4>Summary</h4> Microglia of the developing brain have unique functional properties but how their activation states is regulated is poorly understood. Inflammatory activation of microglia in the still-developing brain of preterm born infants is associated with permanent neurological sequelae in 9 million infants every year. Investigating the regulators of microglial activation in the developing brain with multip...
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Identifiers and source
- Literature Corpus work
- 722ec608-1c4f-5b87-8e8a-522b2977379e
- DOI
- 10.1101/334359