Article

Intracellular force comparison of pathogenic KIF1A, KIF5, and dynein by fluctuation analysis

2021-09-12

Abstract excerpt

In mammalian cells, there exist approximately 40 types of microtubule motor proteins that are assigned to specific cargo deliveries. For example, the kinesin-1 family motor KIF5 is the major motor responsible for anterograde mitochondrial transport, whereas the kinesin-3 family motor KIF1A is responsible for synaptic vesicle precursor transport. In contrast, cytoplasmic dynein is responsible for retrograde transpo...

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Literature Corpus work: d1f973f8-126c-5c74-90a1-332064d0dda6
DOI: 10.1101/2021.09.12.459977

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