Article

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

2022-08-18

Abstract excerpt

<h4>Motivation</h4> Genome-wide association studies (GWAS) have been successful in identifying genetic variants associated with a particular phenotype. However, many complex phenotypes are influenced by multiple genetic variants with small effects. Detecting the genetic pleiotropy can provide insights into biological mechanisms influencing complex human phenotypes. The recently developed Multivariate Omnibus Stat...

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Literature Corpus work: f0a2a47a-38ef-542f-a694-4bb2a2a04e5e
DOI: 10.1101/2022.08.18.504383

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