Article

Rapid Functional Drug Screening of Passage-Zero Patient Brain Tumor Tissues Ex Vivo: Results from a Clinical Feasibility Study

2025-11-04

Abstract excerpt

<title>Abstract</title> <p> Functional precision medicine (FPM) offers a promising path forward in neuro-oncology, where genomic profiling alone often fails to predict therapeutic response. To bridge this gap, we developed the Screening Live Cancer Explants (SLiCE) platform, a rapid <italic>ex vivo</italic> drug screening assay that functionally tests passage-zero patient brain tumor tissues engrafted atop liv...

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Literature Corpus work: d104088c-e721-5439-b6a1-ad42b0ec298b
DOI: 10.21203/rs.3.rs-7993619/v1

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