Article

Generation and biobanking of patient-derived glioblastoma organoids and their application in CAR-T cell testing

2020-03-20

Abstract excerpt

Glioblastoma tumors exhibit extensive inter- and intra-tumoral heterogeneity, which has contributed to poor outcomes of numerous clinical trials and continues to complicate the development of effective therapeutic strategies. Current in vitro models do not preserve the cellular and mutational diversity of parent tumors and often require a lengthy generation time with variable efficiency. Here, we describe detaile...

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Literature Corpus work: d8c42991-59f8-5774-b985-b2767943cf77
DOI: 10.1101/2020.03.19.999110

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