Article

Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion, and drug screening

2023-10-30

Abstract excerpt

<h4>SUMMARY</h4> Brain organoids offer unprecedented insights into brain development and disease modeling and hold promise for drug screening. Significant hindrances, however, are morphological and cellular heterogeneity, inter-organoid size differences, cellular stress, and poor reproducibility. Here, we describe a method that reproducibly generates thousands of organoids across multiple iPSC lines. These High Q...

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Literature Corpus work: 64125731-45c0-5b41-96fb-9d5604557d76
DOI: 10.1101/2023.10.29.564523

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