Article

Macromolecular Diamidobenzimidazole Conjugates Activate STING

2025-01-24

Abstract excerpt

Pharmacologic activation of the stimulator of interferon genes (STING) pathway has broad potential applications, including the treatment of cancer and viral infections, which has motivated the synthesis and testing of a diversity of STING agonists as next generation immunotherapeutics. A promising class of STING agonists are the non-nucleotide, small molecule, dimeric-amidobenzimidazoles (diABZI), which have been...

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Literature Corpus work: d100a32f-5840-5e62-936e-369c0a9bfcea
DOI: 10.1101/2025.01.21.634206

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