Article

STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

2024-03-27

Abstract excerpt

The stimulator of interferon genes (STING) pathway links innate and adaptive antitumor immunity and therefore plays an important role in cancer immune surveillance. This has prompted widespread development of STING agonists for cancer immunotherapy, but pharmacological barriers continue to limit the clinical impact of STING agonists and motivate the development of drug delivery systems to improve their efficacy an...

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Identifiers and source

Literature Corpus work: abfb4e49-3b16-5b53-b626-3ae082a81d22
DOI: 10.1101/2024.03.23.585817

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