Article

Gene dosage effects of polyA track engineered hypomorphs

2021-02-11

Abstract excerpt

<h4>ABSTRACT</h4> The manipulation of gene activity through the creation of hypomorphic mutants has been a long-standing tool in examining gene function. Our previous studies have indicated that hypomorphic mutants could be created by inserting cis-regulatory sequences composed of consecutive adenosine nucleotides called polyA tracks. Here we use polyA tracks to create hypomorphic mutants and functional character...

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Literature Corpus work: d0a0e592-1775-5630-9c4c-f427083b8ac7
DOI: 10.1101/2021.02.10.430645

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