Article

A unified genetic perturbation language for human cellular programming

2025-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Evolution simultaneously and combinatorially explores complex genetic changes across perturbation classes, including gene knockouts, knockdowns, overexpression, and the creation of new genes from existing domains. Separate technologies are capable of genetic perturbations at scale in human cells, but these methods are largely mutually incompatible. Here we present CRISPR-All, a unified genetic p...

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Literature Corpus work: f9d4780c-c555-5d6d-ac6e-2b13ffacb72b
DOI: 10.1101/2025.11.20.689421

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