Article

Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis

2021-04-14

Abstract excerpt

Many host pathogen interactions such as human viruses (including non-SARS-coronaviruses) rely on attachment to host cell-surface glycans. There are conflicting reports about whether the Spike protein of SARS-CoV-2 binds to sialic acid commonly found on host cell-surface N-linked glycans. In the absence of a biochemical assay, the ability to analyze the binding of glycans to heavily- modified proteins and resolve t...

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Literature Corpus work: d080069c-952e-546c-8b77-2bdcd46e31ff
DOI: 10.1101/2021.04.14.439284

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