Article

GLYCO-2: a Tool to Quantify Glycan Shielding of Glycosylated Proteins with Improved Data Processing and Computation Speed

2025-02-27

Abstract excerpt

<h4>Motivation</h4> Glycans bound to glycoproteins mediate immune response, including antibody recognition and immune evasion. Previously, we developed an in silico tool GLYCO (GLYcan COverage) to quantify the glycan shielding of a protein surface, applying it to various studies. However, GLYCO lacks sufficient computational efficiency when analyzing larger datasets. <h4>Results</h4> Here we introduce GLYCO-2...

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Literature Corpus work: d8bbd51e-528b-5a27-ac14-da19d1654435
DOI: 10.1101/2025.02.26.640297

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