Article

Glycan-induced protein dynamics in human norovirus P dimers depend on virus strain and deamidation status

2020-10-07

Abstract excerpt

Noroviruses are the major cause of gastroenteritis and re-emerge worldwide every year, with GII.4 currently being the most frequent human genotype. The norovirus capsid protein VP1 is essential for host immune response. The P domain mediates cell attachment via histo blood-group antigens (HBGAs) in a strain-dependent manner but how these glycan-interactions actually relate to cell entry remains unclear. Here, hydr...

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Literature Corpus work: 2725be7a-8b4c-5842-9cfe-060dd54bdf54
DOI: 10.1101/2020.10.07.329623

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