Article

BBB Dysfunction Defines the Aging Myeloid Landscape Favoring Immune Evasion for Glioma and Alzheimer's Disease

2023-08-07

Abstract excerpt

<title>Abstract</title> <p>The blood-brain barrier (BBB) defines the physiological function of the brain, and it is disrupted in multiple neuropathological diseases. Although vascular abnormalities and BBB leakage characterize the progression of gliomas and occurs in the early stages of Alzheimer's disease (AD), it is unclear their correlation with the neurodegeneration observed in the brain parenchyma. Here, mol...

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Literature Corpus work: d06fbc4a-d630-5a70-8749-2b63b753e9fe
DOI: 10.21203/rs.3.rs-3179089/v1

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