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Glioblastoma and its treatment are associated with extensive accelerated brain aging

17 Jan 2024

Abstract excerpt

Progressive neurocognitive dysfunction is the leading cause of a reduced quality of life in patients with primary brain tumors. Understanding how the human brain responds to cancer and its treatment is essential to improve the associated cognitive sequelae. In this study, we performed integrated transcriptomic and tissue analysis on postmortem normal-appearing non-tumor brain tissue from glioblastoma (GBM)...

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PMID: 38234228
DOI: 10.1111/acel.14066

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