Article
Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer's disease: evidences and perspectives.
Journal of neuroinflammation - 23 Aug 2020
Hasselbalch Hans C, Skov Vibe, Kjær Lasse, Sørensen Torben L, Ellervik Christina, Wienecke Troels
Abstract excerpt
Chronic inflammation and involvement of myeloid blood cells are associated with the development of Alzheimer's disease (AD). Chronic inflammation is a highly important driving force for the development and progression of the chronic myeloproliferative blood cancers (MPNs), which are characterized by repeated thrombotic episodes years before MPN-diagnosis, being elicited by elevated erythrocytes, leukocytes, and...
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