Article

Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

2021-10-19

Abstract excerpt

<h4>ABSTRACT</h4> Neurogenic heterotopic ossifications (NHOs) form in periarticular muscles following severe spinal cord (SCI) and traumatic brain injuries. The pathogenesis of NHO is poorly understood with no effective preventive treatment. The only curative treatment remains surgical resection of pathological NHOs. In a mouse model of SCI-induced NHO that involves a transection of the spinal cord combined with...

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Literature Corpus work: cfd2725f-7879-5c35-b959-4f4f138793a7
DOI: 10.1101/2021.10.19.464906

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