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Burn-induced heterotopic ossification from incidence to therapy: key signaling pathways underlying ectopic bone formation

27 Jul 2021

Abstract excerpt

Burn injury is one of the potential causes of heterotopic ossification (HO), which is a rare but debilitating condition. The incidence ranges from 3.5 to 5.6 depending on body area. Burns that cover a larger percentage of the total body surface area (TBSA), require skin graft surgeries, or necessitate pulmonary intensive care are well-researched risk factors for HO. Since burns initiate such complex...

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PMID: 34315404
DOI: 10.1186/s11658-021-00277-6

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