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Osteoporosis limits neurological recovery after spinal cord injury through PDGF-BB-MMP14 signaling

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Osteoporosis is usually regarded as a downstream skeletal complication of spinal cord injury (SCI), but whether it reciprocally limits spinal cord repair is unclear. We examined the association between bone status and 1-year neurological recovery in a retrospective cohort of 324 patients with traumatic SCI and tested potential mechanisms in mice with ovariectomy-induced osteoporosis fol...

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Literature Corpus work
207c86cb-d81c-5e3a-81a9-fd162ba2e8cb
DOI
10.21203/rs.3.rs-10435457/v1
Open publication

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Osteoporosis limits neurological recovery after spinal cord injury through PDGF-BB-MMP14 signalingDOI 10.21203/rs.3.rs-10435457/v1
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