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Article

Murine Tissue-Resident PDGFRα+ Fibro-Adipogenic Progenitors Spontaneously Acquire Osteogenic Phenotype in an Altered Inflammatory Environment.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2020

Eisner Christine, Cummings Michael, Johnston Gabrielle, Tung Lin Wei, Groppa Elena, Chang Chihkai, Rossi Fabio Mv

Abstract excerpt

Acquired heterotopic ossifications (HO) arising as a result of various traumas, including injury or surgical interventions, often result in pain and loss of motion. Though triggers for HO have been identified, the cellular source of these heterotopic lesions as well as the underlying mechanisms that drive the formation of acquired HO remain poorly understood, and treatment options, including preventative...

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Identifiers

PMID: 32251540
DOI: 10.1002/jbmr.4020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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