Article

SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury

2020-06-02

Abstract excerpt

<h4>Background: </h4> Axonal degeneration is a common pathological feature in many acute and chronic neurological diseases such as spinal cord injury (SCI). SARM1 (sterile alpha and TIR motif containing 1), the fifth TLR (Toll-like receptor) adaptor, has diverse functions in the immune and nervous systems, and recently has been identified as a key mediator of Wallerian degeneration (WD). However, the detailed func...

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Literature Corpus work: edded256-9f22-5d11-8990-4e81c95e62e7
DOI: 10.21203/rs.3.rs-32464/v1

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