Article

Spinal cord injury reprograms muscle fibro-adipogenic progenitors to form heterotopic bones within muscles

2021-11-05

Abstract excerpt

The cells-of-origin of neurogenic heterotopic ossifications (NHO), which develop frequently in the periarticular muscles following spinal cord injuries (SCI) and traumatic brain injuries, remain unclear because the skeletal muscle harbors two progenitor cell populations: satellite cells (SCs) which are myogenic, and fibro-adipogenic progenitors (FAPs) which are mesenchymal. Lineage-tracing experiments using the Cr...

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Literature Corpus work: 123cf56b-e70b-542d-8aa7-52d51103c5f4
DOI: 10.1101/2021.11.04.467192

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