Article

Relating mutational signature exposures to clinical data in cancers via signeR 2.0

2023-04-17

Abstract excerpt

<h4>Motivation</h4> Cancer is a collection of diseases caused by the deregulation of cell processes, which is triggered by somatic mutations. The search for patterns in somatic mutations, known as mutational signatures, is a growing field of study that has already became a useful tool in oncology. Several algorithms have been proposed to perform one or both the following two tasks: 1) de novo estimation of signatu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cf9ef17b-2bb7-5f46-9454-414fd3989383
DOI: 10.1101/2023.04.12.23288466

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Relating mutational signature exposures to clinical data in cancers via signeR 2.0DOI 10.1101/2023.04.12.23288466Read

Relating mutational signature exposures to clinical data in cancers via signeR 2.0.Semantic proximity Read

Computational tools to detect signatures of mutational processes in DNA from tumours: a review and empirical comparison of performanceSemantic proximity Read

BASCULE: Bayesian inference and clustering of mutational signatures leveraging biological priorsSemantic proximity Read

Diffsig: Associating Risk Factors With Mutational SignaturesSemantic proximity Read

signeR: an empirical Bayesian approach to mutational signature discovery.Semantic proximity Read

Detecting presence of mutational signatures in cancer with confidenceSemantic proximity Read

BASCULE: bayesian inference and clustering of mutational signatures leveraging biological priors.Semantic proximity Read

Detecting presence of mutational signatures in cancer with confidenceSemantic proximity Read

Analysis of mutational signatures with yet another package for signature analysis.Semantic proximity Read

Diffsig: Associating Risk Factors with Mutational Signatures.Semantic proximity Read

Accurate and sensitive mutational signature analysis with MuSiCalSemantic proximity Read

Accurate and sensitive mutational signature analysis with MuSiCal.Semantic proximity Read