Article
Computational tools to detect signatures of mutational processes in DNA from tumours: a review and empirical comparison of performance
2018-12-04
Abstract excerpt
Mutational signatures refer to patterns in the occurrence of somatic mutations that reflect underlying mutational processes. To date, after the analysis of tens of thousands of genomes and exomes from about 40 different cancers types, 30 mutational signatures characterized by a unique probability profile across the 96 mutation types have been identified, validated and listed on the COSMIC (Catalogue of Somatic Mut...
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Identifiers and source
- Literature Corpus work
- 7faab50b-4cc8-5b86-80a0-598c0ce4b75f
- DOI
- 10.1101/483982