Article
Analysis of mutational signatures with yet another package for signature analysis.
Genes, chromosomes & cancer - 1 May 2021
Hübschmann Daniel, Jopp-Saile Lea, Andresen Carolin, Krämer Stephen, Gu Zuguang, Heilig Christoph E, Kreutzfeldt Simon, Teleanu Veronica, Fröhling Stefan, Eils Roland, Schlesner Matthias
Abstract excerpt
Different mutational processes leave characteristic patterns of somatic mutations in the genome that can be identified as mutational signatures. Determining the contributions of mutational signatures to cancer genomes allows not only to reconstruct the etiology of somatic mutations, but can also be used for improved tumor classification and support therapeutic decisions. We here present the R package yet another...
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