Article
Accurate and sensitive mutational signature analysis with MuSiCal
2022-04-22
Abstract excerpt
Mutational signature analysis is a recent computational approach for interpreting somatic mutations in the genome. Its application to cancer data has enhanced our understanding of mutational forces driving tumorigenesis and demonstrated its potential to inform prognosis and treatment decisions. However, methodological challenges remain for discovering new signatures and assigning proper weights to existing signatu...
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Identifiers and source
- Literature Corpus work
- 4690aa4e-dfe8-5bcf-aa0d-b2016b9dae0c
- DOI
- 10.1101/2022.04.21.489082