Article

In vivo self-assembled siRNA: a new modality for combination therapy of ulcerative colitis

2021-08-13

Abstract excerpt

<title>Abstract</title> <p>Given the complex nature of ulcerative colitis (UC), combination therapy targeting multiple pathogenic genes and pathways of UC may be required. Unfortunately, current therapeutic strategies based on independent chemical compounds or monoclonal antibodies are not applicable for combination therapy of UC. Here, we developed a synthetic biology strategy that integrates the naturally exist...

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Literature Corpus work: cf9b9460-3957-5831-a959-08ff0a2cbcbd
DOI: 10.21203/rs.3.rs-765327/v1

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