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Article

Nanoparticle-mediated gene therapy strategies for mitigating inflammatory bowel disease

8 Dec 2020

Abstract excerpt

Inflammatory bowel disease (IBD) is an autoimmune disorder of the gastrointestinal tract (GIT) where Ulcerative Colitis (UC) displays localized inflammation in the colon, and Crohn's Disease (CD) affects the entire GIT. Failure of current therapies and associated side-effects bring forth serious social, economic, and health challenges. The gut epithelium provides the best target for gene therapy delivery vehicles...

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PMID: 33404019
DOI: 10.1039/d0bm01359e

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