Article
Programmable Aptamer-Embedded Circular RNAs for Targeted Antigen-Presenting Cells Immunotherapy
2025-09-29
Abstract excerpt
<h4>ABSTRACT</h4> The targeted delivery of mRNA to specific cell types in vivo remains a major unmet need in mRNA-based therapeutics. Conventional strategies rely on nanocarriers engineered with various modifications. However, these exogenous materials could cause adverse reactions, and their complex manufacturing processes often hinder clinical application. By leveraging the innate programmability of RNA sequen...
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Identifiers and source
- Literature Corpus work
- d6099852-eb8c-5a51-b4f4-6575a93e5f20
- DOI
- 10.1101/2025.09.28.679023