Article

Non-cationic RGD-containing protein carrier for tumor-targeted siRNA delivery

2021-06-30

Abstract excerpt

<title>Abstract</title> <p>Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver remains the major hurdle for the widespread application of siRNA in vivo. Current cationic liposome or polymer-based delivery agents are restricted to the liver and suffer from off-target effect, poor clearance, low serum stability, and high toxicity. In this study, we have genetically engineered a no...

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Identifiers and source

Literature Corpus work: f9205622-7399-50a4-89a4-d1741e97c16d
DOI: 10.21203/rs.3.rs-643092/v1

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