Article

Mild deficiency of mitochondrial Complex III in a mouse model of Alzheimer’s disease decreases amyloid beta plaque formation

2021-05-13

Abstract excerpt

<title>Abstract</title> Background: For decades, mitochondrial dysfunctions and the generation of reactive oxygen species have been proposed to promote the development and progression of the amyloid pathology in Alzheimer’s disease, but this association is still debated. In particular, it is still unclear if mitochondrial dysfunctions are a trigger or rather a consequence of the formation of amyloid aggregates...

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Literature Corpus work: cf8c8d99-8884-5816-bb73-bd326b66e653
DOI: 10.21203/rs.3.rs-500142/v1

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