Article

Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates <i>in vivo</i> in a mouse model of Alzheimer’s disease

2022-06-15

Abstract excerpt

<h4>Background</h4> Reactive oxidative stress is a critical player in the amyloid beta (Aβ) toxicity that contributes to neurodegeneration in Alzheimer’s disease (AD). Mitochondrial damage, observed in AD, is one of the main sources of reactive oxygen species. Although Aβ causes neuronal mitochondria-associated reactive oxidative stress in vitro , this has never been directly observed in the in vivo living brai...

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Literature Corpus work: 01976f83-60a2-55b1-8d20-a9faf7eb9138
DOI: 10.1101/2022.06.12.495840

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Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates <i>in vivo</i> in a mouse model of Alzheimer’s diseaseDOI 10.1101/2022.06.12.495840Read

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