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High-resolution dissection of human cell type-specific enhancers in <i>cis</i> and <i>trans</i> activities

2023-09-24

Abstract excerpt

The spatiotemporal specific gene expression is regulated by cell type-specific regulatory elements including enhancers, silencers and insulators etc. The massively parallel reporter assay (MPRA) methods like STARR-seq facilitate the systematic study of DNA sequence intrinsic enhancer activities in a large scale. However, when applied to human cells, it remains challenging to identify and quantify cell type-specifi...

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Literature Corpus work
cf5ebeaf-b18b-515e-b80e-9febb14739f9
DOI
10.1101/2023.09.23.559140
Open publication

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High-resolution dissection of human cell type-specific enhancers in <i>cis</i> and <i>trans</i> activitiesDOI 10.1101/2023.09.23.559140
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