Article

Novel Roles of G-quadruplexes on Enhancers in human chromatin

2021-07-12

Abstract excerpt

G-quadruplexes (G4), stable four-stranded non-canonical DNA structures, are highly related to function of promoters and initiation of gene transcription. We found that G4 structures were also enriched in the enhancers across different cell lines. However, the relationship between G4 structures and enhancer activity remains unknown. Here, we proved that G4 structures on enhancers lead to the re-positioning of nucle...

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Literature Corpus work: 4bf01a3d-812b-5a41-9d5f-96f10203ee6e
DOI: 10.1101/2021.07.12.451993

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