Article

Camptothecin regulates microglia polarization and exerts neuroprotective effects via the AKT/Nrf2/HO-1-NF-κB signal axis in vivo and in vitro

2020-07-23

Abstract excerpt

<title>Abstract</title> <p>Background Parkinson's disease (PD), the second largest neurodegenerative disease seriously affects human health. Microglia, the main immune cells in the brain participate in the innate immune response in the central nervous system (CNS). Studies have shown that microglia can be polarized into pro-inflammatory M1 and anti-inflammatory M2 phenotypes. Accumulated evidences suggest that o...

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Literature Corpus work: cf0a6cbb-8722-5232-9585-c45d53ff4e56
DOI: 10.21203/rs.3.rs-46120/v1

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