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Pharmacological Blocker of NF-κb and Mitochondrial Ros Restrict NLRP3 Inflammasome Activation and Rescue Dopaminergic Neurons in Vitro and in Vivo Parkinson’s Disease

2021-03-03

Abstract excerpt

<title>Abstract</title> <p>Several activators of NLRP3 inflammasome have been described; however, the central mechanisms of NLRP3 inflammasome activation in brain microglia, especially at the activating step through free radical generation, still require further clarification. Hence the present study aimed to investigate the role of free radicals in activating NLRP3 inflammasome driven neurodegeneration and eluci...

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Literature Corpus work
c670b8fc-021f-51c9-9096-cc1e9808bc8b
DOI
10.21203/rs.3.rs-260478/v1
Open publication

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Pharmacological Blocker of NF-κb and Mitochondrial Ros Restrict NLRP3&nbsp;Inflammasome Activation and Rescue Dopaminergic Neurons in Vitro and in Vivo Parkinson’s DiseaseDOI 10.21203/rs.3.rs-260478/v1
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