Article

Levistilide A Exerts a Neuroprotective Effect by Suppressing Glucose Metabolism Reprogramming and Preventing Microglia Polarization Shift

2024-01-26

Abstract excerpt

The microglia, displaying diverse phenotypes, play a significant regulatory role in the development, progression, and prognosis of Parkinson's disease. Research has established that glycolytic reprogramming serves as a critical regulator of inflammation initiation in pro-inflammatory macrophages. Furthermore, the modulation of glycolytic reprogramming has the potential to reverse the polarized state of these...

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Literature Corpus work: 2e6f9291-113e-5fd2-b961-c7f91078dee8
DOI: 10.20944/preprints202401.1921.v1

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