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Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's disease

1 Apr 2025

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative disorder, which is characterized by the death of dopaminergic neurons. It has been reported that ceftriaxone (CEF) exerts promising effects on alleviating dopaminergic neuron death in PD models. However, the neuroprotective mechanisms of CEF in PD have not been well understood. In the present study, to investigate the neuroprotective effects of...

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PMID: 40183389
DOI: 10.3892/ijmm.2025.5526

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