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Luteolin blocks dopaminergic neuron degeneration and shifts microglial M1/M2 polarization by inhibiting Toll like receptor 4

2024-01-30

Abstract excerpt

<h4>Background: </h4> Luteolin is a natural flavonoid, and its neuroprotective and anti-inflammatory effects have been confirmed to mitigate neurodegeneration. Despite these findings, the underlying mechanisms responsible for these effects remain unclear. Toll-like receptor 4 (TLR4) is widely expressed in microglia and plays a pivotal role in neuroinflammation and neurodegeneration. Here we outline studies aimed a...

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Literature Corpus work
3f6ed9a6-99a0-56ef-a628-ba24cc72518f
DOI
10.22541/au.170663883.39174238/v1
Open publication

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Luteolin blocks dopaminergic neuron degeneration and shifts microglial M1/M2 polarization by inhibiting Toll like receptor 4DOI 10.22541/au.170663883.39174238/v1
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