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Article

Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases

14 May 2017

Abstract excerpt

Microglia are the resident innate immune cells of the central nervous system that mediate brain homeostasis maintenance. Microglia-mediated neuroinflammation is a hallmark shared by various neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Numerous studies have shown microglial activation phenotypes to be heterogeneous; however, these microglial phenotypes can...

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PMID: 28555105
DOI: 10.3389/fnagi.2017.00139

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