Article

Standing HA phenotypic breadth shapes H5N1 cross-host potential

2026-07-21

Abstract excerpt

<title>Abstract</title> <p>Linking genetic variation to functional phenotype remains a major barrier to assessing the cross-host potential of emerging viruses. Here, we reconstruct the evolution of predicted hemagglutinin (HA) phenotypic traits across ~13,000 highly pathogenic avian influenza A H5N1 clade 2.3.4.4b viruses circulating in North America. The wide geographic spread of avian influenza within North Ame...

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Literature Corpus work: cebfa36b-c2d9-55ae-8bf2-34c2073f0bee
DOI: 10.21203/rs.3.rs-10349790/v1

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