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Avian influenza virus neuraminidase stalk length and haemagglutinin glycosylation patterns reveal molecularly directed reassortment promoting the emergence of highly pathogenic clade 2.3.4.4b A (H5N1) viruses

2024-05-22

Abstract excerpt

<h4>ABSTRACT</h4> The recently emerged panzootic clade 2.3.4.4b H5N1 influenza viruses show unprecedented extensive spread in wild birds and have been transmitted to several mammals, including humans. The virologic factors that have driven the success of the 2.3.4.4b H5N1 viruses, which has not been achieved by previous H5N1 clades, is unclear. We show that the 2.3.4.4b H5 haemagglutinin (HA) paired exclusively w...

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Literature Corpus work
fa8d60ee-4ba2-5ae9-bcff-28f2bf5e3bd2
DOI
10.1101/2024.05.22.595329
Open publication

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Avian influenza virus neuraminidase stalk length and haemagglutinin glycosylation patterns reveal molecularly directed reassortment promoting the emergence of highly pathogenic clade 2.3.4.4b A (H5N1) virusesDOI 10.1101/2024.05.22.595329
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