Article

Distinctive viral genome signatures are linked to repeated mammalian spillovers of H5N1 in North America

2025-12-09

Abstract excerpt

Highly pathogenic avian influenza H5N1 rarely infects mammals. In 2024–2025, however, genotypes B3.13 and D1.1 caused two independent spillovers into U.S. dairy cattle. By analysing 26,930 complete H5N1 genomes from global surveillance, we identified 73 major viral groups, most of which show continent-specific distribution in Europe, Asia, Africa, and North America. North American viruses exhibit higher genetic di...

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Literature Corpus work: 5d33508b-f180-5b95-bfdf-9a46d3ec4ad6
DOI: 10.64898/2025.12.09.693147

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